소아 혈액종양 연구실은 최고 수준의 전문가들이 협업하여 암에 대한 정확한 진단, 각각의 환자에게 알맞는 적절한 최상의 치료를 목표로 최선의 연구를 수행하고 있습니다.
오랜 치료 경험뿐 아니라 보다 나은 치료를 위해 다양한 연구와 임상 시험을 선도적으로 진행하고 있습니다.
향후 면역세포유전자치료 등 부작용이 적은 치료의 개발을 통해 항암제 없이 소아 환자를 치료하는 세상을 만들기 위해 노력하고 있습니다.

Baek GW, Yun SO, Park MY, Kang HJ. “Generation of antigen-specific T lymphocytes targeting Wilms tumor 1 using activated B cells.”, Hum Immunol. 2023 Feb;84(2):106-112.

Loeb DM, Lee JW, Morgenstern DA, Samson Y, Uyttebroeck A, Lyu CJ, Van Damme A, Nysom K, Macy ME, Zorzi AP, Xiong J, Pollert P, Joerg I, Vugmeyster Y, Ruisi M, Kang HJ. “Avelumab in paediatric patients with refractory or relapsed solid tumours: dose-escalation results from an open-label, single-arm, phase 1/2 trial.” Cancer Immunol Immunother. 2022 Oct;71(10):2485-2495.

Hong KT, Park HJ, Kim BK, An HY, Choi JY, Kang HJ. “PTCy-based Haploidentical vs Matched Unrelated Donor Peripheral Blood HSCT Using Myeloablative Targeted Busulfan-based Conditioning for Pediatric Acute Leukemia. Transplant Cell Ther.” 2022 Apr;28(4):195.e1-195.e7.

Lee S, Hong KT, Moon SJ, Choi JY, Hong CR, Shin HY, Cho JY, Jang IJ, Yu KS, Oh J, Kang HJ. “Pharmacokinetic and Pharmacodynamic Characteristics of Tripegfilgrastim, a Pegylated G-CSF, in Pediatric Patients with Solid Tumors.“, Clin Pharmacol Ther., 2022. Jan, 111(1):293-301.

Choi JY, Kim H, Baek HJ, Kook H, Lee JM, Kim BK, An HY, Hong KT, Shin HY, Kang HJ., “Open-label, Multicenter Phase II Study of Combination Therapy of Imatinib Mesylate and Mycophenolate Mofetil in pediatric patients with Steroid-Refractory Sclerotic/fibrotic Type Chronic Graft-versus-host disease.” Transplant Cell Ther., 2021 Nov, 27(11):925.e1-925.e7.

Lee S, Shin CH, Lee J, Jeong SD, Hong CR, Kim JD, Kim AR, Pak B, Son S, Kokhan O, Yoo T, Ko JS, Sohn YB, Kim OH, Ko JM, Cho TJ, Wright NT, Seong JK, Jin SW, Kang HJ, Kim HH, Choi M.,” Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome.”, Blood., 2021 Nov, 138(21):2117-2128.

Park HJ, Hong KT, Yun SO, Ahn HY, Choi JY, Shin HY, Kang HJ., “Successful Treatment of refractory CMV colitis after haploidentical HSCT with post-transplant cyclophosphamide using CD45RA+ depleted donor lymphocyte infusion.” Bone Marrow Transplant., 2020 Aug, 55(8):1674-1676.

Lee GH, Hong KT, Choi JY, Shin HY, Lee WW, Kang HJ. “Immunosenescent characteristics of T cells in young patients following haploidentical haematopoietic stem cell transplantation from parental donors.     Clin Transl Immunology.,     2020 Apr, 9(4):e1124.