암연구소 소개
"Enhancement of Gene Editing and Base Editing with Therapeutic Ribonucleoproteins through In Vivo Delivery Based on Absorptive Silica Nanoconstruct"Advanced Healthcare Materials DOI: 10.1002/adhm.202201825 (2022).
"Voyage to minimal base editors" Nature Chemical Biology 18(9), 920-921 (2022).
"Therapeutic base editing and prime editing of COL7A1 mutations in recessive dystrophic epidermolysis bullosa" Molecular Therapy 30(8), 2664-2679 (2022). (Front cover)
"Comprehensive analysis of prime editing outcomes in human embryonic stem cells" Nucleic Acids Research 50(2), 1187-1197 (2022).
"In vivo gene editing via homology-independent targeted integration for adrenoleukodystrophy treatment" Molecular Therapy 30(1), 119-129 (2022).
"Quantitative assessment of engineered Cas9 variants for target specificity enhancement by single-molecule reaction pathway analysis" Nucleic Acids Research 49, 11312-11322 (2021).
"High-purity production and precise editing of DNA base editing ribonucleoproteins" Science Advances 7(35), eabg2661 (2021).
"Adenine base editors engineering reduces editing of bystander cytosines" Nature Biotechnology 39(11), 1426-1433 (2021).
"Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease" Cell Stem Cell 28(9), 1614-1624 (2021). (Front cover)
"PE-Designer and PE-Analyzer: Web-based design and analysis tools for CRISPR prime editing" Nucleic Acids Research 49(W1), W499–W504 (2021).
"Current status and challenges of DNA base editing tools" Molecular Therapy 28(9), 1938-1952 (2020).
"Adenine base editors catalyze cytosine conversions in human cells" Nature Biotechnology 37(10), 1145–1148 (2019).
"Direct observation of DNA target searching and cleavage by CRISPR-Cas12a" Nature Communications 9, 2777 (2018).
"Digenome-seq web tool for profiling CRISPR specificity" Nature Methods 14(6), 548–549 (2017).
“Structural roles of guide RNA in the nuclease activity of Cas9 endonuclease” Nature Communications 7, 13350 (2016).