[ 논문 ]
● Radiosensitivity is associated with antitumor immunity in estrogen receptor-negative breast cancer. Kang BH, Jang BS, Kim IA. Breast Cancer Res Treat 2023;197(3):479-488.
● Combination of OX40 Co-Stimulation, Radiotherapy, and PD-1 Inhibition in a Syngeneic Murine Triple-Negative Breast Cancer Model. Han MG, Wee CW, Kang MH, Kim MJ, Jeon SH, Kim IA. Cancers 2022;14(11):2692.
● PI3Kγδ inhibitor plus radiation enhances the antitumor immune effect of PD-1 blockade in syngenic murine breast cancer and humanized patient-derived xenograft model. Min Guk Han, Bum-Sup Jang, Mi Hyun Kang, Deukchae Na, In Ah Kim. European Journal of Cancer 2021 in press
● PI3Kalphaδ inhibitor combined with radiation enhances the antitumor immune effect of anti- PD1 in a syngeneic murine triple negative breast cancer model. Jang WI, Han MK, Kang MH, Park JM, Kim EE, Bae JY, Ahn S, Kim IA. Int J Radiat Oncol Biol Phys 2021; 110(3):845-858
● Tumor mutation burden, immune checkpoint crosstalk and radiosensitivity in single-cell RNA sequencing data of breast cancer. Jang BS, Han W, Kim IA. Radiother Oncol. 2020:142:202-209
● A radiosensitivity gene signature and PD-L1 status predict clinical outcome of patients with glioblastoma multiforme in The Cancer Genome Atlas Dataset. Jang BS, Kim IA. Cancer Res Treat 2019:52(2):335-354
● A radiosensitivity gene signature and PD-L1 predict the clinical outcomes of patients with lower grade glioma in TCGA. Jang BS, Kim IA. Radiother Oncol. 2018;128(2):245-253.
● Inhibition of PI4K IIIα radiosensitizes in human tumor xenograft and immune-competent syngeneic murine tumor model. Park Y, Park JM, Kim DH, Kwon J, Kim IA. Oncotarget 2017; 30;8(66):110392-110405

● A radiosensitivity gene signature and PD-L1 status predict clinical outcome of patients with invasive breast carcinoma in The Cancer Genome Atlas (TCGA) dataset. Jang BS, Kim IA. Radiother Oncol 2017; 124:403-407
● Targeting phosphatidylinositol 4-kinase IIIα for radiosensitization: a potential model of drug repositioning using anti-HCV agent. Kwon J, Kim DH, Park JM, Park YH, Hwang YH, Wu HG, Shin KH, Kim IA. Int J Radiat Oncol Biol Phys 2016; 96:867-876
● MicroRNA-200c increases radiosensitivity of human cancer cells with activated EGFR-associated signaling. Koo T, Cho. BJ, Kim DH, Park JM, Choi EJ, Kim HH, Lee DJ and Kim IA. Oncotarget 2017;8(39): 65457-65468
● Radiosensitizing effect of lapatinib in human epidermal growth factor receptor 2-positive breast cancer cells. Yu T, Cho BJ, Choi EJ, Park JM, Kim DH, Kim IA. Oncotarget 2016;7(48): 79089- 79100
[ 특허 ]
● Modulation of radiation response using microRNAs
● Composition for enhancing radiation sensitivity comprising PI4K isozyme inhibitor
● Method for treating triple negative breast cancer combined with radiotherapy comprising administering phosphatidylinositol 3-kinase inhibitor and PD-1 blockade