Our laboratory studies endocrine tumors such as parathyroid glands and adrenal glands, in particular, thyroid cancer. The laboratory is located at Seoul National University's Cancer Research Institute. We have been constantly contemplating about creating a laboratory that can integrate basic and clinical research. Endocrine tumor biobank was established from the beginning of the establishment of the laboratory, and human specimens such as thyroid, parathyroid, and adrenal glands have been collected. The Biobank has more than 7,000 samples, including blood, urine, hair and cancer tissues of various endocrine tumors, normal tissue of the same patient. Moreover, BioBank is still growing in size and quality with more than 7,000 samples at present. Since Biobank was established, it has been conducting next-generation sequencing research using human cancer tissues and has been discovering new candidates for thyroid cancer-causing genes. Bioinformatics is the latest trend in biology, and in particular, next-generation sequential big data such as TCGA (The Cancer Genome Atlas) is being released as public data, so that the high quality research can be conducted in everywhere. Our laboratory also has been actively verified several our biologic data which containing next-generation sequencing data, clinical genetic data, and gene expression found in vitro experiment by comparing with the public biologic data. In addition to Bioinformatics, in vitro and in vivo experiments are also being actively conducted. Firstly, we conduct in vitro experiments to identify characteristics of cells (patterns of growth, metastasis, mobility and etc.) with a cell-line harboring certain mutation. And then, we proceed animal experiments to more clarify our hypothesis by checking up growth of tumors, drug sensitivity, and immune cell profiling as well as survival analysis, if necessary. We keep our efforts in order to apply excellent results from studies conducted at “Bench” to “Bedside” New entrants can be encouraged to conduct basic experiments, and have opportunities of discussing with our experts about the analysis of advanced bioinformatics.